As the central metabolic organ, the liver is exposed to considerable stress around calving (transit phase). A cow quickly slides into ketosis, bringing far-reaching consequences. Discover the role played by the liver and how this important organ needs to be protected here.
- What is ketosis in cows?
In veterinary medicine, ketosis is defined as the increased formation of acetone, a metabolic product, in the blood. Read more
- How can I tell if a cow has ketosis?
Ketosis can be divided into a sub-clinical and clinical phase. Read more
- How does ketosis develop?
Feeding the high-performance cow is a tightrope walk between ketosis and acidosis. Read more
- How much does ketosis in cows cost me?
Financial damage due to ketosis is caused, among other things by reduced feed intake. Read more
- Caution fatty liver! What is the role of the liver in ketosis?
High production potential of today’s genetics inevitably lead to a negative energy balance in early lactation. Read more
- DairySafe - so that the liver does not become fatty and sluggish!
The special feed JOSERA DairySafe with the LSP active ingredient package supports you so that the cow does not suffer liver damage. Read more
- What is LSP?
DairySafe contains the innovative active agent package, LSP (Liver safety package). Read more
- How does DairySafe work?
Read more about the mode of action of JOSERA DairySafe. Read more
- How and when do I use DairySafe?
Read more about the feeding recommendation for the product JOSERA DairySafe. Read more
- What advantages does my herd have from DairySafe?
An improvement of the liver health and a higher milk yield result from feeding DairySafe. Read more
- What advantages do I benefit from as a farmer through DairySafe?
Healthier animals and profitability are two advantages that you get from JOSERA DairySafe. Read more
- What experiences have farmers had with DairySafe?
Read more about colleagues which already use DairySafe. Read more
- Which JOSERA product line does DairySafe belong to?
In veterinary medicine, ketosis is defined as the increased formation of acetone, a metabolic product, in the blood. Ketosis, also referred to as acetonemia, is a disorder of energy metabolism. It is the most important metabolic disease of the dairy cow and occurs 90% of the time during early lactation, the period with the highest energy deficit.
As the central metabolic organ, the liver is exposed to severe stress around the birth period (transit phase). A reducing feed intake is accompanied by an increasing need. This need can be very heavily or often not at all covered by the feed intake at the latest after the birth. A high-performance cow inevitably has to melt down body substance to compensate for the lack of nutrients.
In many animals in this case, the melted fat cannot be integrated into the energy metabolism because the glucose required for this is also deficient. As a result, the cow slides into a ketosis.
Ketosis is one of the most common metabolic diseases of today's high performance cows and leads to considerable economic losses.
Ketosis can be divided into a sub-clinical and clinical phase. The following symptoms are not immediately visible in cows suffering from sub-clinical ketosis:
- firmer dung or diarrhoea
- no desire to eat
On the other hand, the clinical symptoms are concrete and can directly indicate ketosis:
- acetone smell
- shinier and concentrated to disc-shaped dung
- wobbly walk
Are you unsure whether your cow has ketosis?
Test the blood, urine or milk of the cow.
Feeding the high-performance cow is a tightrope walk between ketosis and acidosis. Because of the rapid increase in milk yield after calving, there is a high milk sugar release. There is also a high energy requirement for milk protein synthesis. The aim is to transform the negative energy balance into a positive one by the 50th day of lactation.
Cows are able to compensate part of the energy deficit by breaking down body fat. The use of body energy reserves of up to 25% is possible.
The rapid mobilisation of body fat promotes the development of metabolic disorders. Excessive mobilisation prevents the liver from metabolising all free fatty acids. The consequences are fatty degeneration of the liver and ketosis, which in turn favour other diseases such as mastitis, ovarian cysts, claw diseases, and endometritis.
If a cow has ketosis, this can entail the following costs:
- a single treatment (infusion set, time, etc.):
|glucose drench*||5.00 €|
|propylene glycol (sodium-propionate) shot approx. 200 g||1.00 €|
|Kexxtone Bolus||40.00 €|
|ketosis treatment (veterinarian)||60.00 €|
|calcium drench*||5.00 €|
- loss of performance
- higher morbidity
- culling rate
In total, costs of €200 to €400 can be incurred per ketosis and animal. If these costs are extended across several cows, it can lead to high economic problems.
High production potential of today’s genetics inevitably lead to a negative energy balance in early lactation. In this period the liver is extremely stressed. The consequence frequently is a ketosis or the development of a fatty liver.
The liver is the central metabolic organ, as shown by the following figure.
An overloaded liver can no longer function properly. Therefor your cows become more vulnerable to disease – especially ketosis.
Therefore, it is important to protect the liver and to prophylactically prevent liver damage. Learn how this is possible in the next section.
The special feed JOSERA DairySafe with the LSP active ingredient package supports you so that the cow does not suffer liver damage.
DairySafe helps the liver to detoxify ammonia, form urea, detoxify bilirubin and detoxify medication.
In addition DairySafe leads to:
- lower susceptibility to disease
- better fertility
- higher feed intake for high performance
- lower culling rate
DairySafe contains the innovative active agent package, LSP, the liver safety package.
A specific combination of rumen-protected active agents support the liver‘s functions. The excess fat can be removed or be metabolised better by the body.
LSP is the active ingredient package with biologically active substances that supports the liver function and stabilises the metabolism in the perinatal phase.
- concentrated effectiveness
- rumen-protected active substances
- synergy effects (physiological advantages)
- much cheaper than individual substances
… reduces fat mobilisation
… supports gluconeogenesis and increases the blood sugar level
… degreases the liver and supports its performance
The following images make the effect clear.
Figure 1: The thickness of back fat in the transit phase could be increased by DairySafe.
Figure 2: The content of β-Hydroxybutyric acid in blood (BHB) could be reduced.
DairySafe is a special mixture for dairy cows:
- three weeks before until five weeks after birth: up to 200g per day/animal
- for the rest of the lactation period (up to 90 days): 100 to 200g per day, in order to support the metabolism and achieve high output
- more efficient liver
- higher milk yield
- higher profit through healthy animals
- the animals are much healthier:
- better fertility
- conservation and improvement of liver health
- high profitability
- more milk
- lower vet costs
- improved restocking
- you save time and money!
- €300 per ketosis (milk loss, treatment, complications)
- no metabolic and secondary diseases
- better fertility
- disposals due to metabolic problems
Many farmers are already using DairySafe with complete satisfaction and the results are clear to see! At a North Hessian farm with 600 Holstein Friesians, the ketoses were able to be reduced from 20% to 5%. The cows now calve again and can be milked more easily.
What led to this experience?
Prior to the use of DairySafe, the animals were fed propylene glycol. With the help of a blood test, 20% of ketoses could be determined and documented in the herd management system.
DairySafe was then mixed into the total mixed ration 21 days before and 14 days after the birth of the cows with 200g per animal and day.
The result: the ketoses were able to be reduced from 20% to 5%.
In addition, 1.6 tons of expensive propylene glycol was saved.
Here you can find the complete experience report of the farm as a video:
JOSERA DairySafe is part of the PERFORMANCE line from JOSERA. The products in the PERFORMANCE line are innovative, powerful and serve the achievement of ambitious business goals.
Read more about the various product lines and how they can be used here.
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